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World Sickle Cell Day 2019: Key Facts, Theme, History and Symptoms of this disease

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World Sickle Cell Day is celebrated with the help of Government, non-government organisations and different Health agencies. This day give individuals a superior thought regarding the sickle cell disease. Government compose a few battles to urge individuals to focus on the sickle cell disease for their legitimate fix and security for the general population who are not suffering from it.

What is Sickle Cell Disease?

Sickle cell disease or sickle cell anaemia is an inherited form of anaemia in which red blood cells are not able to carry adequate oxygen throughout the body. Let us tell you that in normal condition red blood cells are flexible and round. They move easily in the blood vessels. But in sickle cell disease or anaemia, the red blood cells become rigid, sticky and become like sickle shape or crescent moon. As a result these irregular shaped cells get stuck in small blood vessels, which slow the flow of blood or block blood flow and reduce oxygen to reach the parts of the body.

World Sickle Cell Day: History

World Sickle Cell Day was organised by United Nation as General Assembly in 2008 to raise the mindfulness about the sickle cell disease and the agony that individuals go for the duration of the life. On 19 June, 2009, it was first time celebrated. These days, sickle cell illness has turned into a typical hereditary malady that spread all around the globe. In this manner, it is necessary to cure through the fast awareness campaign, curable activities, early diagnosis and management. Even, World Health Organisation promotes several activities in the world to resolve the issue of haemoglobin dysfunction.

As per the statistics, consistently in excess of 1000 children are taking birth with sickle cell disease in the Africa and getting die as long as five years old. In the United States more than 90,000 to 100,000 individuals are influenced with this disease. Not only this, even in the countries like India, Saudi Arabia, Turkey, Arabic peninsula, Brazil, Surinam, Guiana, Southern Italy, Greece etc. people are suffering from sickle cell anaemia. No doubt it is big health issue which is to be resolved or to take control over it for healthy future of the nation. Due to Sickle Cell disease, the premature child death has been raised in the world.

Sickle Cell Anemia: Key Facts

– The disease is depicted as sickle because the red blood cells are sickle or crescent-shaped and anaemia means lack of blood.

– Sickle cell anaemia disease influences a huge number of individuals around the globe.

– Sickle cell anaemia disease is inherited and not contagious.

– There is no definitive cure for sickle cell anaemia. However, it can be prevented by the pre-marital screening.

– Let us tell you that there is a difference sickle cell anaemia and iron-deficiency anaemia.

– Do you realize that like any sound individuals, patients experiencing sickle cell weakness don’t build up any sort of indications?

In this way, World Sickle Cell Day is celebrated by discharging booklet, blurbs, featuring the various parts of sickle cell disease. Plus, this few rivalries are additionally sorted out by the organised like “Healthy Child” competition along with felicitation of senior citizens affected by sickle cell disease.

World Sickle Cell Day is seen to spread mindfulness among individuals around the world about the sickle cell anaemia disease and its treatment methods. It is an inherited genetic abnormality of haemoglobin in which the oxygen carrying protein found in red blood cells.

The signs and symptoms of this disease are as follows:

1. Loss of red blood cells: Characteristic of sickle cell anaemia, the red cells lose their round circle like shape, to turn into much progressively like sickles because of an absence of hemoglobin in the body. In addition to the fact that this makes the cells more fragile, however it likewise makes them less adaptable and stiffer. This reduces the oxygen carrying capacity of the blood.

2. Random pains: The agonies happening in various pieces of the body frequently turned out to be unusual. This is because of the blood vessels getting blocked and a lack of oxygen in that part of the body. If the body isn’t able to harness all the oxygen it needs, it will prioritise, and certain parts of the body will not get sufficient oxygen. This causes acute pains.

3. Fatigue and breathlessness: It is very normal for those suffering from sickle cell anaemia to experience extreme tiredness, weakness and an overall lack of energy. This is primarily due to the lack of oxygen supply to the body to break down for energy.

4. Jaundice: The white of the eyes, and the skin turns yellowish. This is on the grounds that, a sickle cell dies far speedier and quicker than an ordinary cell. As the liver endeavors to separate the dead cells, a side-effect called Bilirubin develops, causing the yellow colour.

5. Urinary issues: Infections are regular among patients of this disease. They may face inconvenience in the creation of urine (thought or weaken) and there have been a few examples of blood in the urine as well. The bladder and urinary tract must be regularly tested for the breeding of infections.

6. Inflammation: As blood vessels get blocked, either by dead sickle cells, or just an overall lack of red blood cells and oxygen supply, the body parts tend to swell up. This inflammation often occurs in the fingers and toes of the infected individual. This also causes tissue damage in the inflamed part of the body.

The treatments for this ailment shift by seriousness. No fix exists, however its effects can be slowed down with medical help. We urge you to spread awareness about this disease among your friends, family and colleagues and seek out ways in which you can help and contribute.

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Alex Matos has been acquired by Chelsea from Norwich City.

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Equipped for playing in midfield and assault, Matos highlighted for Norwich’s Under-18s and Under-21s last season. For the latter, he scored three goals in the Premier League 2.

Matos, who played for England as a schoolboy, moved to Norwich from Luton Town in 2016. Shortly after turning 16, he scored in his first appearance for the Canaries’ youth team against Arsenal.

The 18-year-old found the middle value of an objective contribution for each game – five objectives, six helps – in his initial 11 appearances at that level and turned into an ordinary for Norwich’s Under-18s during the 2022/23 mission, in which he was likewise given his presentation for the Under-21s.

Welcome to Chelsea, Alex!

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In Washington, hydrogen-powered aviation and sustainable fuel startups announce plans for expansion.

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This week, the Paris Air Show began with announcements from two sustainable aviation ventures expanding their efforts in Washington state.

The hydrogen-powered aviation startup ZeroAvia has announced that it will expand its R&D capabilities at its Paine Field facility in Everett. ZeroAvia will receive a $350,000 grant from the state Department of Commerce to support the project, doubling the state’s previous investment. Last month, the organization praised an organization with Gold country Carriers to retrofit a resigned plane with its drive framework.

Twelve, a company developing sustainable aviation fuel, announced that it is constructing a commercial-scale production facility in Moses Lake, Eastern Washington. Twelve uses carbon dioxide and water to make a synthetic jet fuel, drawing comparisons to photosynthesis. When compared to conventional fossil fuels, it reduces greenhouse gas emissions by 90% and powers its process with renewable energy.

The air show in Le Bourget, France, lasts for a whole week, and a Washington delegation of nearly two dozen businesses and organizations is there to talk about the state’s role in sustainable aviation and get new businesses interested in flying into the Pacific Northwest.

Technology is in high demand everywhere. A global coalition of commercial airlines made a pledge two years ago to achieve net zero carbon emissions by 2050. Shipping companies and other businesses also want to cut emissions.

Willie Walsh, director general of the International Air Transport Association, addressed a Boeing-led conference near Seattle this spring and stated, “We recognize that this is going to be extremely challenging, but it is achievable and we are absolutely determined to do everything we can to achieve that goal.” The conference was held near Seattle.

The petroleum fuels that power the majority of airplanes make it impossible to go green in aviation because there are no alternatives that come close to matching their affordability, availability, weight, or sheer amount of energy. Strategies for reducing carbon include:

Fuel for sustainable aviation (SAF): Feedstock materials include crops, sewage and dairy waste, waste vegetable oils, and agricultural and forestry debris.
Hydrogen: This fuel can be made from water and methane, among other things, and burnt directly or in fuel cells.
Batteries: Due to the batteries’ “energy density,” or weight in relation to the power generated, this option is currently restricted to smaller aircraft flying shorter distances.
Operations and materials modifications: NASA awarded Boeing a $425 million, seven-year grant to develop and test ultra-thin-winged fuel-efficient aircraft. Flight plans are being modified to reduce fuel consumption by airlines, cargo companies, and others.
Contrail studies: The ice cloud clouds produced by engine exhaust are unpredictable contrails. The Contrail Impact Task Force was established last year to investigate contrail impacts and opportunities for reduction.
It’s a lot to think about. The Cascade Climate Impact Model, a free tool released by Boeing last month, is intended to assist businesses in evaluating the cost-benefit trade-offs of various approaches to lowering carbon emissions, possibly with the intention of including Boeing aircraft in the solutions.

SAF is being favored by many established aerospace interests, particularly in the near future. It is possible to use the fuel in aircraft that already exist by mixing it with jet fuel. Boeing authorities refer to SAF as “the greatest switch” for cutting aeronautics carbon. However, the fuel is in short supply, accounting for well less than 1% of the total jet fuel that is currently available.

Senior emerging technology analyst Jonathan Geurkink of PitchBook seems to agree that SAF is the best option, at least for the time being. Today, “it’s a plug-and-play kind of solution for a lot of different reasons,” Guerkink stated. We don’t want to dump all of these planes at once.

Twelve signed a memorandum of understanding with Microsoft and Alaska Air last year to support the startup’s technology development in addition to the announced expansion in Moses Lake. Microsoft hopes to use Twelve’s fuel to offset employee travel costs, while Alaska intends to test it in one of its aircraft.

Locally, the sector is receiving additional support. In the spring of this year, lawmakers in Washington approved a bill that created a tax incentive for locally produced SAF and approved funding for a sustainable aviation fuel R&D center at Paine Field. In May, the Dutch company SkyNRG said it would build a biogas plant in Washington to make environmentally friendly aviation fuel.

“Assuming that motivating forces are adjusted suitably, there is feedstock, there’s innovation — everything that are set up to create practical flying fuel,” said John Dees, a senior decarbonization researcher with Carbon Direct. ” It concerns costs. It continues to cost more.

Numerous businesses are looking into alternative fuel options, despite the fact that SAF has an advantage in cleaner aviation. This includes: in the Pacific Northwest:

ZeroAvia, with offices in California and the UK and research and development facilities in Everett.
In order to develop its aircraft, Universal Hydrogen, a California company, collaborates with AeroTEC, based in Seattle, and MagniX, based in Everett. Universal Hydrogen tested its hydrogen-powered electric propulsion system on a plane called Lightning McClean in March at Moses Lake.
Eviation, a company with headquarters in Arlington, Wash., completed a successful test flight of its all-electric Alice aircraft in Moses Lake in September 2022.
Personal aviation startup Zeva Aero is based in Tacoma, Wash., and its planned products include battery-powered aircraft.
However, clean hydrogen fuel is also in short supply, just like SAF. Additionally, because hydrogen is expensive and difficult to transport, some people consider producing it close to where it is used. In order for battery-powered flight to succeed, weight reduction efforts must continue.

There are a lot of good reasons to believe that hydrogen and batteries won’t be really viable for a while. Dees stated, “It’s not just a question of whether it works in the plane; the airports would need to adopt a lot of infrastructure.”

However, despite the obstacles, hydrogen and batteries are “where things will go,” he added.

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When the new Adipurush poster featuring Prabhas and Kriti Sanon was unveiled on Ram Navami, the internet commented, “It doesn’t look promising”

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Following the film’s team’s release of the new Adipurush poster on Ram Navami, Instagram users commented that it “doesn’t look promising.”

On Thursday, a brand-new poster for Adipurush, the masterpiece of filmmaker Om Raut, was revealed. Prabhas posted the poster on Instagram, portraying Ram, Sita, and Laxman alongside Kriti Sanon and Sunny Singh. Hanuman was depicted in the poster bowing in front of the trio as they were posed together.

Kriti stated in a recent interview with news outlet PTI about Adipurush, “It is a movie of which the complete team is incredibly proud. I sincerely expect and pray that others will share my pride in it. To all of us, it is something very essential. Simply put, it is much more than a movie to us. I hope it gets its due. I have a feeling it will. It is important to make these stories. It is educational for kids. I feel if I had not seen it then, today’s children would also have not seen it.”

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