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It is possible to develop mRNA vaccines for TB, dengue, and other diseases, say Indian scientists who accepted the Nobel Prize for medicine

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Two scientists, Hungarian-born American Katalin Karikó and American Drew Weissman, received the Nobel Prize in medication on Monday for discoveries that enabled the introduction of mRNA vaccines in opposition to Covid-19 and that ought to be used to boost different photographs in the future.

Welcoming the news, scientists in India stated this method should be used for the improvement of vaccines and therapeutics for a range of different ailments inclusive of tuberculosis or dengue. Rajesh Gokhale, Secretary in Department of Biotechnology, stated the Nobel Prize used to be a well timed cognizance for the mRNA based totally vaccines.

“The manner in which cells reply and apprehend special mRNA, it can be used to prompt the immune system. Differences in mRNA had been attributed to chemical changes through nucleoside and this differential property was once utilised for the improvement of vaccines in the course of Covid-19,” Gokhale said.

The company’s Gemcovac-19 used to be rolled out solely in 2022, and the Gemcovac-Om, a booster vaccine particular to the Omicron variant, was once brought until now this year.

By this time, most of the Indian populace had already been vaccinated against Covid19, however Singh stated it used to be extraordinarily necessary that a vaccine based totally on this science was once innovated in India and reached the market.

Dr Vinod Paul, member, the National Institution for Transforming India (NITI Aayog),said the mRNA pathway for vaccines has opened new doors.

“mRNA technological know-how can be deployed for vaccines towards TB, dengue, foot and mouth disease, Nipah, Zika, etc., and certainly for novel redress for infections and cancers. This is an epoch-making technological know-how and Indian scientists have mastered it with improvements. India additionally produced the world’s first human DNA vaccine.The R&D of each the mRNA and DNA vaccines was once supported by means of authorities funding via mission Covid Suraksha.” Dr Paul instructed media.

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Reels can be downloaded by anyone if your account is public on Instagram

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Short-form movies are all the rage these days, and each social media platform is in on it. Instagram launched Reels a few years ago, and they’re hugely popular. However, there is a privateness issue, as Instagram is now permitting all of us to down load Reels from bills that are public.

Yes, all people can down load your Reels if your Instagram profile is public. Instagram boss Adam Mosseri printed that the choice to down load Reels has been stay in the US considering that June 2023, however all people in the world can now use this feature. Prior to this, human beings would have to use third-party equipment and internet browser extensions to down load Reels, however Instagram is now providing the characteristic natively. This would enhance facts protection for these downloading these short-form videos, however it should be a privateness nightmare for these who at the beginning uploaded the Reel.

In a current announcement, Instagram CEO Adam Mosseri published that customers round the globe can now down load Instagram Reels from public bills at once to their digital camera roll. The feature, at the start brought in the United States in June, has passed through beta checking out and is now accessible for iOS and Android users.

The characteristic is comparable to the down load performance accessible on TikTok, giving customers get entry to to the down load alternative beneath the share button. To shield the work of the authentic creator, the downloaded Reels are in addition saved in the gallery of the device, watermarked with the authentic poster’s Instagram username.

The replace universally applies to all public accounts, enabling everyone on Instagram to down load and share Reels except the account proprietor modifies their down load settings. For Instagram customers underneath the age of 18 with public accounts, the down load characteristic is at the beginning deactivated, however they hold the flexibility to set off it at their convenience.

In the professional FAQ, Instagram set up regulations to protect the privateness and accessibility of Reels. It notes that account privateness settings will play a pivotal function in figuring out the accessibility of Reels downloads to different users.

In the case of public accounts, Reels can be downloaded by using any Instagram user. The down load settings can be customised for unique posts or the whole account. However, for customers below 18 with public accounts, the down load function is in the beginning disabled by means of default, giving them the choice to allow it later.

On the contrary, for non-public accounts, Reels downloads are restricted. This skill that no one on Instagram can get entry to the content material until the account proprietor chooses to change their privateness putting to public.

Meanwhile, Instagram is presenting public account holders the potential to control their down load settings. This will supply them with the manage to figure out whether or not or no longer their followers can down load their Reels. Instagram similarly notes that in the case of public accounts, solely newly created reels can be downloaded except there are changes to the down load settings. The downloaded reels will encompass an Instagram watermark, the username of the authentic poster, and audio attribution. Furthermore, the unique audio from a reel is eligible to be blanketed in a downloaded reel only if the authentic reel containing that unique audio is downloadable.

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A list of the 10 most popular Indian stars published by IMDb features Shah Rukh Khan at the top, followed by Alia Bhatt and Deepika Padukone

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Shah Rukh Khan has already made two blockbuster films, ‘Pathan’ and ‘Jawan’, and this year he is planning to release his third film, ‘Dunki’ directed by Rajkumar Hirani.

IMDb on Wednesday announced the top 10 most popular Indian stars of 2023. This list is the first of its kind and is based on actual page views from IMDb’s more than 200 million monthly visitors worldwide. Shah Rukh Khan, who became his IMDb number 1 star in India in 2023, starred in two blockbuster films (Pathan and Jawan) this year, sparking unprecedented global fan interest.

Alia Bhatt has secured the 2nd place for the second year in a row, and her two blockbusters in 2023 are ‘Rocky Our Rani Ki Prem Kahaani’ and ‘Heart of Stone’. I starred in the release. She also made her Met Gala debut earlier this year and won an Oscar and a Golden Globe for Best Original Song for her 2022 film RRR.

Alia Bhatt thanks her fans and says, “IMDb is a true representation of the choices of our viewers. I have always said they are the true kings and queens and nothing can surpass them.” I would like to thank the viewers for putting me in this position.I will continue to entertain them, but I am filled with love and gratitude.I also wish to continue my efforts in the future. We are committed to continuing to bring more inspiring stories and characters to the screen.”

Wamiqa Gabi said about making it to IMDb’s final top 10 list for the first time. The fact that IMDb reflects the mood of viewers around the world makes this even more special to me. From Vishal Bhardwaj’s spy thriller ‘Kuffiya’ and Vikramaditya Motwane’s historical drama ‘Jubilee’ to the heartwarming web series ‘Modern Love Chennai’ to the Punjabi film ‘Kali Jotta’, I love the genre I’ve had a busy year working across languages. That makes me happy. I’m happy and grateful that my fans appreciated it. I look forward to working on future projects with the same dedication and repaying the love you have shown me. ”

Nayanthara made her Hindi film debut with Shah Rukh Khan in Jawan (No. 1), while she made her Hindi film debut with Deepika Padukone (No. 3). She also co-starred with Shah Rukh in Pathaan and Jawan. Padukone’s appearance on the eighth season of the talk show ‘Koffee with Karan’ along with her husband Ranveer Singh also became a hot topic.

Tamannaah Bhatia (No. 6) worked across regions, languages ​​and platforms. She appeared in the streaming films ‘Lust Stories 2’, ‘Jee Karda’ and ‘Aakhri Sach’, also starred in the theatrical release ‘Bholaa Shankar’ and had a cameo in ‘Jailer’.

Kareena Kapoor Khan (7th place) made her OTT debut with Jaan Jaan and her film The Buckingham Murders had its world premiere at the BFI London Film Festival.

Vijay Sethupathi (No. 10) made his double debut this year with his first Hindi film ‘Jawan’ and his first Indian web series ‘Farzi’.

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Iraqi forces backed by Iran are killed in a US strike

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A US warplane killed multiple Iranian-backed militiamen in Iraq after they fired a short-range ballistic missile at American and allied personnel in the country, the Pentagon said on Tuesday.

“We can confirm an attack last night by Iran-backed militias using a close-range ballistic missile against US and coalition forces at Al-Asad Airbase, which resulted in eight injuries and some minor damage to infrastructure,” Pentagon spokesman Brigadier General Pat Ryder said in a statement.

“Immediately following the attack, a US military AC-130 aircraft in the area conducted a self-defense strike against an Iranian-backed militia vehicle and a number of Iranian-backed militia personnel involved in this attack. This self-defense strike resulted in several enemy KIA (killed in action),” Ryder said.

The United States on Wednesday carried out retaliatory precision strikes against two facilities in Iraq, the US military said.

“U.S. Central Command forces conducted discrete, precision strikes against two facilities in Iraq,” a statement from the US military said.

“The strikes were in direct response to the attacks against U.S. and Coalition forces by Iran and Iran-backed groups, including the one in Iraq on November 21, which involved use of close-range ballistic missiles,” the statement added.

The strike reportedly hit a vehicle belonging to a pro-Iranian group in a convoy travelling through Abu Ghraib, 30 kilometers west of Baghdad.

The Pentagon earlier confirmed an attack by Iran-back militias against US and coalition forces at Al-Asad Airbase in Iraq`s Western Anbar province. The airbase hosts forces of the US-led coalition fighting the Islamic State (IS) group in Iraq. Pentagon spokesman Brigadier General Pat Ryder said that the attack resulted in “eight injuries and some minor damage to infrastructure”.

“Immediately following the attack, a US military AC-130 aircraft in the area conducted a self-defense strike against an Iranian-backed militia vehicle and a number of Iranian-backed militia personnel involved in this attack. This self-defense strike resulted in several enemy KIA (killed in action),” Ryder said.

Deputy Pentagon Press Secretary Sabrina Singh told reporters in Washington that US forces “have been attacked approximately 66 times since October 17 -32 separate times in Iraq and 34 separate times in Syria.”

Singh said the militants were targeted in Iraq “because the AC-130 was able to determine the point of origin from where the close-range ballistic missile was… fired to the base” and then tracked the militants in their vehicle.

One Iranian-backed fighter was killed and three others injured in the attack.

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